The reference site for Metronidazole

Metronidazole (MNZ), marketed under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis.

WHAT IS METRONIDAZOLE?

Metronidazole is a man-made drug that is effective against certain bacteria and parasites (protozoa). It is used for treating vaginal infections with protozoa such as Trichomonas vaginalis, ameba, and giardia and also is effective against anaerobic bacterial infections (anaerobic bacteria are a type of bacteria that grow without oxygen).

Metronidazole is also used in the treament of the dermatological condition rosacea, where it is marketed by Galderma under the trade names Rozex® and MetroGel®.

 

Brand Name(s): Flagyl; MetroCream; MetroGel;
MetroGel-Vaginal
CAS nº: 443-48-1
(me-troe-NI-da-zole)

Product Info

The sections below will provide you with more specific information and guidelines related to metronidazole and its correct use. Please read them carefully.

FDA Information

Metronidazole was approved by the FDA in 1963.

Metronidazole is approved for the treatment of amebic dysentery, amebic liver abscess, trichomoniasis anaerobic infection, bacterial vaginosis, and rosacea.

Off-lable, it is also indicated for antibiotic induced pseudo membranous enterocolitis and giardiasis.

Why is this medication prescribed?

Metronidazole is a man-made drug that is effective against certain bacteria and parasites (protozoa). It is used for treating vaginal infections with protozoa such as Trichomonas vaginalis, ameba, and giardia and is also effective against anaerobic bacterial infections (anaerobic bacteria are a type of bacteria that grow without oxygen).

Metronidazole is also used in the treament of the dermatological condition rosacea.

Other uses for this medicine

Metronidazole is also used alone or in combination with other antibiotics in treating abscesses in the liver, pelvis, abdomen and brain caused by susceptible anaerobic bacteria.

Metronidazole is also used in treating colon infection caused by a bacteria called C. difficile.

However, it is important that you first talk to your doctor about the possible risks of using this drug for your particular condition.

Dosage and using this medicine

USAGE

Metronidazole gel:

Do not use this medicine in or near the eyes. Watering of the eyes may occur when the medicine is used too close to the eyes.

If this medicine does get into your eyes, wash them out immediately, but carefully, with large amounts of cool tap water. If your eyes still burn or are painful, please consult this with your doctor.

Before applying this medicine, thoroughly wash the affected area(s) with a mild, nonirritating cleanser, rinse well, and gently pat dry.

Capsule, tablet, and injection:

Take metronidazole exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

To help clear up your infection completely, keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

In some kinds of infections, this medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times, day and night. For example, if you are to take 4 doses a day, the doses should be spaced about 6 hours apart. If this interferes with your sleep or other daily activities, or if you need help in planning the best times to take your medicine, check with your health care professional

DOSAGE

The usual treatment of rosacea is by application of metronidazole gel twice daily.

The usual dose of the vaginal form of metronidazole gel is one full applicator (containing 37.5mg of metronidazole) intravaginally twice daily for 5 days. It should be applied once in the morning and once in the evening.

NOTE: metronidazole is metabolized mainly by the liver and dosages may need to be reduced in patients with abnormal liver function.

What special precautions should I follow?

BEFORE TAKING METRONIDAZOLE:

Tell your doctor if you have liver disease, a stomach or intestinal disease, or epilepsy or another seizure disorder.

You may not be able to take metronidazole, or you may require a lower dose or special monitoring during your therapy, if you have any of these conditions.

Metronidazole is in the FDA pregnancy category B. This means that it is not likely to harm an unborn baby. Do not, however, take metronidazole without first talking to your doctor if you are pregnant.

Furthermore, this medication passes into breast milk and may affect a nursing infant, so do not take this medication without first talking to your doctor.

Do not drink alcohol while taking metronidazole.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.

Never take a double dose to make up for a missed one.

What side effects can this medication cause?

Possible side effects from metronidazole include:

diarrhea
dizziness or lightheadedness
headache
loss of appetite
nausea or vomiting
stomach pain or cramps

Tell your doctor if any of these symptoms are severe or do not go away:

nausea, vomiting, or loss of appetite
an unpleasant metallic taste in your mouth
constipation or mild diarrhea
headache
swollen or sore tongue

If you experience any of the following symptoms, call your doctor immediately:

an allergic reaction (swelling of your lips, tongue, or face; shortness of breath; closing of your throat; or hives)
seizures
numbness or tingling
dizziness or loss of coordination
severe diarrhea

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Always keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Throw away any medication that is outdated or no longer needed and talk to your pharmacist about the proper disposal of your medication, should it be necessary.

In case of an emergency/overdose

In case of an overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

nausea
vomiting
dizziness
loss of coordination
numbness and seizures

 

Product Images

PICTURES OF METRONIDAZOLE PILLS

Below you will find images and specific information on the principal types of metronidazole that exist, including their respective brand name(s), strength, inscription codes and manufacturers.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Name: METRONIDAZOLE
Strength(s): 250 MG
Imprint: Z 2971
Manufacturer: IVAX PHARMACEUTICALS

Name: METRONIDAZOLE
Strength(s): 250 MG
Imprint: PLIVA 333
Manufacturer: PLIVA INC.

Name: METRONIDAZOLE
Strength(s): 250 MG
Imprint: Z 2971
Manufacturer: SIDMAK LABS.

Name: METRONIDAZOLE
Strength(s): 250 MG
Imprint: 93 | 851
Manufacturer: TEVA USA

Name: FLAGYL®
Strength(s): 375 MG
Imprint: FLAGYL 375 mg
Manufacturer: PHARMACIA/UPJHN.

Name: METRONIDAZOLE
Strength(s): 375 MG
Imprint: A 353
Manufacturer: ABLE LABS.

Name: FLAGYL®
Strength(s): 500 MG
Imprint: FLAGYL | 500
Manufacturer: PHARMACIA/UPJHN.

Name: METRONIDAZOLE
Strength(s): 500 MG
Imprint: PLIVA 334
Manufacturer: PLIVA, INC.

Name: METRONIDAZOLE
Strength(s): 500 MG
Imprint: 852 | 933
Manufacturer: TEVA USA

Name: METROCREAM®
Strength(s): 0.75%
Imprint: MetroCream Topical 0.75%
Manufacturer: GALDERMA

Name: METROGEL-VAGINAL®
Strength(s): 0.75%
Imprint: MetroGel-Vaginal 0.75% Vaginal Gel
Manufacturer: 3M PHARM.

Name: METRONIDAZOLE
Strength(s): 0.75%
Imprint: METRONIDAZOLE Topial Cream 0.75%
Manufacturer: FOUGERA

Name: NORITATE®
Strength(s): 1%
Imprint: Noritate Cream, 1% Topical
Manufacturer: AVENTIS PHARM.

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